ABx Advantage

State of the Art Antibiotic Resistance Detection

Misuse and overuse of antimicrobials is one of the world’s most pressing public health problems. Infectious organisms adapt to the antimicrobials designed to kill them, making the drugs ineffective. People infected with antimicrobial-resistant organisms are more likely to have longer, more expensive hospital stays, and may be more likely to die as a result of an infection. Improving the way we prescribe and use antibiotics, or “antibiotic stewardship,” is critical to effectively treat infections, protect patients from harms caused by unnecessary antibiotic use, and combat antibiotic resistance.
Antimicrobial stewardship provides critical diagnostic information to make better drug choices, leading to fewer adverse effects and reducing the cost of treatment. The antimicrobial stewardship report powered by Arkstone Medical Solutions is based on scientific evidence. It helps select the best drug choices, optimum doses, shorter treatment length, and best administration route.
In the case of multidrug-resistant organisms, antimicrobial, stewardship-based treatment options can save lives, reduce hospitalization cost, drug toxicity, and the duration of treatment. The goal of antimicrobial stewardship is to select the best drug for treating a wild pathogen organism. Without proper antimicrobial stewardship, multiple drug usage can result in resistance. Multidrug-resistant organisms or superbugs are a global challenge; according to CDC, more than 2 million U.S. citizens are infected with MDRO multidrug resistant pathogens, resulting in approximately 23,000 deaths.

Clinical Need :

  • Continuous exposure to antibiotics can result in bacteria becoming resistant
  • More and more antibiotics %re becoming ineffective against bacteria
  • 6 of the 18 most alarming antibiotic resistance threats are Vancomycin resistant Enterococcus, Carbapenem resistant Acinetobacter species, Methicillin resistant Staphylococcus aureus (MRSA) Carbapenem resistant Enterobacterales (CRE), Extended-spectrum cephalosporin resistance in Enterobacterales and multidrug resistant Pseudomonas aeruginosa.
  • Antibiotic resistance cost the US more than $4.6 billion annually

~2.8 million people get an antibiotic-resistant infection annually

~35,000+ individuals die from antibiotic resistant infections annually

wound (5)

ABx Advantage

The main reason for providing antimicrobial stewardship (ASP) is to educate and guide physicians to make better drug choices which leads to less adverse effects and a reduction in the cost of treatment. The antimicrobial stewardship report powered by Arkstone Medical Solutions is based on scientific evidence and helps in selecting the best drug choices, optimum doses, shorter length of treatment and best route of administration. In the case of multidrug-resistant organisms (MDROs) antimicrobial stewardship-based treatment options can save lives, reduce hospitalization cost, drug toxicity and the duration of treatment. The goal of ASP is to select the best drug for treating a wild pathogen organism, without proper ASP multiple drug usage can result in the emergence of resistance. Multidrug-resistant organisms or superbugs are a global challenge; according to CDC each year more than 2 million US citizens are infected with MDROs resulting in approximately 23,000 deaths.

Clinical Need:

  • Continuous exposure to antibiotics results in bacteria becoming resistant
  • More and more antibiotics are becoming ineffective against bacteria
  • Worldwide, ~30% of drug prescriptions equaling a total of 47 million prescriptions are unnecessary
  • ASP helps in making the right drug choices and proper doses on a patient-by-patient basis

ABx Advantage

The Absolute Genomics ABx Advantage gene panel is designed to detect significant classes of antibiotic resistance. In addition, this panel can identify the presence of specific resistance genes that are involved in drug inhibition. The Absolute Genomics ABx Advantage gene panel has 11 antibiotic resistance genes belonging to aminoglycosides, β-lactamase, fluoroquinolone, macrolide, tetracycline, vancomycin, and multi-drug resistance classifications. The data is used for providing antibiotic resistance stewardship via Arkstone Medical Solutions. The one-choice report powered by Arkstone Medical Solutions for the ABx Advantage gene panel converts PCR data into simple interpretations for physicians to help them make better treatment decisions. This technology is a combination of software artificial intelligence and human expertise.

  • The antimicrobial report contains a unique ArkScore to help prescribers make informed decisions
  • The antimicrobial decision engine combines machine-learning artificial intelligence with decades of deep infectious disease expertise to guide physicians to a singular treatment regimen that targets the most relevant infection with the lowest risk to the patient.
  • ArkScore describes the level of antimicrobial resistance expressed in organisms.
  • ArkScore provides the most effective treatment with the least risk of adverse events resulting in the reduction of unnecessary use of broad-spectrum antibiotics

Extensive Panel List

lorem ipsum Panel List

  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ
  • XYZ