Nail

State of the Art Nail Pathogen Detection

The Absolute Genomics Nail InSITE panel is a comprehensive RT-PCR panel with 17 bacterial and fungal targets. In addition to pathogen diagnoses, this panel also detects antibiotic resistance gene markers. The test detects multiple pathogens and antibiotic resistance in a single PCR workflow. This highly actionable information is provided in a simple, efficient report with the best available drug choice.
The Absolute Genomics Nail InSITE panel will rapidly multiply millions of copies of DNA from a pathogen to determine what bacteria or fungus is in the specimen. The emergence of identifying fungal pathogens in nail tissue may take the guesswork out of treating fungal infections, allowing doctors to begin targeted. The specimens are obtained by simply trimming small pieces of a nail. PCR testing can produce accurate results in hours while traditional culturing could take days to weeks.

Clinical Need :

  • Onychomycosis is a common disease of the nail and is the cause of roughly 50% of nail deformities
  • Onychomycosis affects approximately 14-18% of people living in the USA
  • Laboratory testing is important to aid in identifying the pathology of the nail deformation to determine a proper treatment plan
  • Co-infections can be detected by PCR based testing allowing for multiple treatments
  • Traditional culturing methods for fungi and bacteria have turnaround times of days to weeks while our PCR turnaround time is under 24 hours for both pathogen and antibiotic resistance detection

5% of patients with diabetes mellitus develop foot ulcers with 1% resulting in amputation

~15% of older adults in the U.S. suffer from chronic wounds

nail
5% of patients with diabetes mellitus develop foot ulcers with 1% resulting in amputation
5% of patients with diabetes mellitus develop foot ulcers with 1% resulting in amputation
~15% of older adults in the U.S. suffer from chronic wounds
~15% of older adults in the U.S. suffer from chronic wounds

ABx Advantage

The Absolute Genomics ABx Advantage gene panel is designed to detect significant classes of antibiotic resistance. In addition, this panel can identify the presence of specific resistance genes that are involved in drug inhibition. The Absolute Genomics ABx Advantage gene panel has 11 antibiotic resistance genes belonging to aminoglycosides, β-lactamase, fluoroquinolone, macrolide, tetracycline, vancomycin, and multi-drug resistance classifications. The data is used for providing antibiotic resistance stewardship via Arkstone Medical Solutions. The one-choice report powered by Arkstone Medical Solutions for the ABx Advantage gene panel converts PCR data into simple interpretations for physicians to help them make better treatment decisions. This technology is a combination of software artificial intelligence and human expertise.

  • The antimicrobial report contains a unique ArkScore to help prescribers make informed decisions.
  • The antimicrobial decision engine combines machine-learning artificial intelligence with decades of deep infection disease expertise to guide physicians to a singular treatment regimen that targets the most relevant infectiona with the lowest risk to the patient.
  • ArkScore describes the level of antimicrobial resistance expressed in organisms.
  • ArkScore provides the most effective treatment with the least risk of adverse events resulting in the reduction of unnecessary use of broad-spectrum antibiotics

Extensive Panel List

Bacteria Enterobacter cloacae Enterococcus faecalis Enterococcus faecium Escherichia coli Klebsiella pneumoniae Pseudomonas aeruginosa Staphylococcus aureus Enterobacter aerogenes

Bacteria

  • Enterobacter cloacae
  • Enterococcus faecalis
  • Enterococcus faecium
  • Escherichia coli
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa
  • Staphylococcus aureus
  • Enterobacter aerogenes
Fungi Candida parapsilosis Candida tropicalis Candida albicans Candida glabrata Trichophyton mentagrophytes var. interdigitale Trichophyton mentagrophytes var. menta Trichophyton rubrum Trichophyton tonsurans Trichophyton verrucosum

Fungi

  • Candida parapsilosis
  • Candida tropicalis
  • Candida albicans
  • Candida glabrata
  • Trichophyton mentagrophytes var. interdigitale
  • Trichophyton mentagrophytes var. menta
  • Trichophyton rubrum
  • Trichophyton tonsurans
  • Trichophyton verrucosum
Viruses HSV1 HSV2

Viruses

  • HSV1
  • HSV2
Bacteria Enterobacter cloacae Enterococcus faecalis Enterococcus faecium Escherichia coli Klebsiella pneumoniae Pseudomonas aeruginosa Staphylococcus aureus Enterobacter aerogenes

Bacteria

  • Enterobacter cloacae
  • Enterococcus faecalis
  • Enterococcus faecium
  • Escherichia coli
  • Klebsiella pneumoniae
  • Pseudomonas aeruginosa
  • Staphylococcus aureus
  • Enterobacter aerogenes
Fungi Candida parapsilosis Candida tropicalis Candida albicans Candida glabrata Trichophyton mentagrophytes var. interdigitale Trichophyton mentagrophytes var. menta Trichophyton rubrum Trichophyton tonsurans Trichophyton verrucosum

Fungi

  • Candida parapsilosis
  • Candida tropicalis
  • Candida albicans
  • Candida glabrata
  • Trichophyton mentagrophytes var. interdigitale
  • Trichophyton mentagrophytes var. menta
  • Trichophyton rubrum
  • Trichophyton tonsurans
  • Trichophyton verrucosum

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